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Anti-diarrhoeal activity of Butea monosperma in experimental animals.

Gunakkunru A, Padmanaban K, Thirumal P, Pritila J, Parimala G, Vengatesan N, Gnanasekar N, Perianayagam JB, Sharma SK, Pillai KK

Department of Pharmacology, K.P. College of Pharmacy, Thiruvannamalai, India.

The anti-diarrhoeal potential of the ethanolic extract of stem bark of Butea monosperma (Lam) Kuntz has been evaluated using several experimental models in Wistar albino rats. The extract inhibited castor oil induced diarrhoea and PGE(2) induced enteropooling in rats; it also reduced gastrointestinal motility after charcoal meal administration. The results obtained establish the efficacy and substantiate the use of this herbal remedy as a non-specific treatment for diarrhoea in folk medicine.

Published 7 April 2005 in J Ethnopharmacol, 98(3): 241-4.
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